Medicin

Medicin til Narkolepsi

Medicin til Katapleksi

Medicin  (Ritalin) mod Hyperaktivitet under mistanke for at give hjerteproblemer..... LÆS MERE


Compounds

Usual Daily Dose

Notes

Stimulants
Modafinil: Provigil® 100-400mg Fewer sympathomimetic effects and side effects, long duration of action, well tolerated but lower potency than amphetamines
Methylphenidate-HCl: Ritalin®, RitalinSR® (extended release) 10-60mg The regular formulation has a very short duration of action. This is often useful when patients want to tailor their treatment to their daily activities or combine stimulant medication with sheduled napping.
Dextroamphetamine-Sulfate: Dexedrine®, Dextrostat®, Dexedrine-SR® 5-60mg Variable duration of action (Urinary pH and formulation), used in the US
Methamphetamine-HCl: Desoxyn@ 5-60mg Better distribution in the brain vs. the periphery, more potent and effective than amphetamine, used in the U.S.
Pemoline: Cylert® 20-115mg Less potent and effective, long duration of action, hepatotoxicity
Mazindol: Sanorex® 0.5-6mg Weakly effective, rarely used except in the U.K.
Anticataplectic Compounds
Venlafaxine: EffexorSR® 75-225mg New antidepressant, slow release formulation, acting on both the serotoninergic and adrenergic system, active on cataplexy; limited clinical experience but positive preliminary results
Atomoxetine: Strattera® 10-80mg Norepinephrine reuptake inhibitor
Protriptyline: Triptil®, Vivactil® 5-60mg Anticholinergic effects (dry mouth, blurred vision, constipation, etc.) at high doses, mild stimulant, preferentially adrenergic effects
Imipramine: Janimine@, Tofranil® 10-100mg Anticholinergic effects
Desipramine: Norpramin®, Pertofran® 25-100mg Same as imipramine but more adrenergic effects
Clomipramine: Anafranil® 10-150mg Very effective, mostly used in Europe
Fluoxetine: Prozac® 20-60mg Også kaldet lykkepiller
Reboxetine: Edronax® 2-10mg Nyt antidepresiv middel som bl.a. er virksomt mod katapleksi
Hypnotic Compounds
Sodium Oxybate: Xyrem® 3-9g Short duration of action, resulting anticatapletic effects during daytime. Helps alleviate daytime sleepiness. Was approved on July 17, 2002.
Hypnotic Benzodiazepines Same as for the treatment of non-narcoleptic insomnias

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